Gabapentin (Neurontin): Medication for Epilepsy and Neuropathic Pain

Drug Name: Generic Neurontin
Tablet Strength: 100mg, 300mg, 400mg, 600mg, 800mg
Price: $0.60
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Prescription Required: Gabapentin (Neurontin®) is a Schedule V prescription medication in the United States.

Overview:

Gabapentin, marketed under the brand name Neurontin, is a prescription medication used to treat epilepsy and neuropathic pain. It helps reduce nerve pain and prevents seizures.

Uses and Dosage:

Gabapentin is commonly used to treat neuropathic pain and epilepsy. The dosage and treatment plan should always be determined by a healthcare professional. Typically, for neuropathic pain, starting doses range from 100-300 mg per day, gradually increasing based on tolerance. For epilepsy, the dosage varies depending on age and condition.

Gabapentin: common oral dose schedules (adults)
Indication Starting dose Titration Max daily
Post-herpetic neuralgia 300 mg QHS × 1 ↑ to 300 mg TID over 3 days 1 800 mg
Partial seizures 300 mg TID ↑ every 3 days by 300 mg TID 3 600 mg
Diabetic neuropathy † 300 mg QHS ↑ q 3–5 days as tolerated 2 400 mg
† Off-label but guideline-supported use3

Retail price check (28 Jun 2025): 90 caps of 300 mg gabapentin cost $11 – $17 with a free GoodRx coupon.
Prices vary by pharmacy and state.

Contraindications and Precautions:

Do not use Gabapentin if you are allergic to any of its components or have severe kidney impairment. Pregnant or breastfeeding women should consult their doctor before starting this medication. Caution is advised if you have a history of depression or substance abuse.

Potential Side Effects:

Gabapentin may cause side effects like dizziness, fatigue, or headaches. Seek immediate medical attention if you experience severe symptoms such as mood changes or difficulty breathing.

Drug Interactions:

Gabapentin may interact with other medications, including opioids and antacids. Make sure your healthcare provider is aware of all medications or supplements you are taking.

Storage Instructions:

Store Gabapentin at room temperature, away from excess moisture and light. Keep it out of reach of children.

Important Warning:

Gabapentin is a prescription medication. Consult a healthcare provider before starting treatment to ensure it’s safe and appropriate for your condition.

Additional Resources:

For more information, refer to the medication guide provided by the manufacturer or consult your healthcare provider.

References

  1. U.S. Food & Drug Administration. Neurontin® (gabapentin) – Highlights of Prescribing Information. NDA 021129. 2023 Update.
  2. Backonja M et al. Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus. JAMA. 1998;280(21):1831-36. doi:10.1001/jama.280.21.1831
  3. Bril V, England J, Franklin GM et al. Evidence-based guideline: treatment of painful diabetic neuropathy. Neurology. 2011;76(20):1758-65.